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| Genre/Form: | Electronic books |
|---|---|
| Additional Physical Format: | Printed edition: |
| Material Type: | Document, Internet resource |
| Document Type: | Internet Resource, Computer File |
| All Authors / Contributors: |
Hiroshi Yamazaki |
| ISBN: | 9784431549925 4431549927 4431549919 9784431549918 |
| OCLC Number: | 882557693 |
| Notes: | Includes index. |
| Description: | 1 online resource (ix, 409 pages) : illustrations (some color) |
| Contents: | Preface -- Part 1 Cytochrome P450 History -- 1 Pioneers in the Early Years of Cytochrome P450 Research -- 2 Fifty Years of Progress in Drug Metabolism and Toxicology: What Do We Still Need to Know About Cytochrome P450 Enzymes? -- 3 Fifty Years of Cytochrome P450 Research: Examples of What We Know and Don{u2019}t Know -- Part 2 Structure, Function, and Practical Applications of P450 -- 4 Cytochrome P450 Dynamics -- 5 Structural and Functional Diversity of Cytochrome P450 -- 6 Oxygenation of Non native Substrates Using a Malfunction State of Cytochrome P450s -- 7 Plant Cytochrome P450s in Triterpenoid Biosynthesis: Diversity and Application to Combinatorial Biosynthesis -- 8 Mammalian and Bacterial Cytochromes P450 Involved in Steroid Hydroxylation: Regulation of Catalysis and Selectivity and Potential Applications -- 9 Neurosteroids: Regional Steroidogenesis -- 10 Whole Cell-Dependent Biosynthesis of Drug Metabolites Using Genetically Engineered Budding Yeast -- 11 Metabolic Diversity and Cytochromes P450 of Fungi -- 12 Metabolic Engineering of Flower Colour Pathways Using Cytochromes P450 -- Part 3 Gene Regulation of P450 -- 13 Aryl Hydrocarbon Receptor Suppresses Cecal Carcinogenesis -- 14 Epidermal Growth Factor Receptor: The Phenobarbital Receptor That Elicits CAR Activation Signal for P450 Induction -- 15 Steroidogenic Cytochrome P450 Gene CYP11A1: Functions and Regulation -- 16 Cooperative Regulation of Expression of Cytochrome P450 Enzymes by Aryl Hydrocarbon Receptor and Vitamin D Receptor -- Part 4 Drug Metabolism -- 17 Species, Ethnic and Individual Differences in Human Drug-Metabolizing Cytochrome P450 Enzymes -- 18 Cytochrome P450-Depedent Change in UDP- Glucuronosyltransferase Function and Its Reverse Regulation -- 19 Control of Xeno/Endobiotics-Metabolizing Cytochrome P450s by Micro RNAs -- 20 The Pharmacogenomics of Cytochrome P450s: From Molecular to Clinical Application -- 21 Cytochrome P450 Polymorphisms of Clinical Importance -- BM Epilogue -- Index. |
| Responsibility: | Hiroshi Yamazaki, editor. |
| More information: |
Abstract:
Fifty Years of Cytochrome P450 Research
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